Nutrition is a cornerstone of the Indian healing system of Ayurveda. It emphasizes the relationship between food, health and well-being. Rasayana is a vital component of Ayurveda that results in rejuvenation and preventive health care. Its holistic approach not only seeks to enhance physical well-being but also addresses mental and spiritual health, reflecting Ayurveda's comprehensive understanding of human health. Nithyam Ksheera Ghritabhyasa is a foundational Ayurvedic practice that promotes the daily consumption of milk and ghee, which are considered as sattvic foods. It promotes purity, strength, mental clarity and rejuvenate the body. Milk, which is rich in nutrients like protein and calcium supports bone health, enhances digestion and boosts immunity. Ghee, known for its nourishing properties, aids in detoxification and promotes mental clarity. Together, these foods helps to improve overall vitality and support the body’s natural rhythm. Incorporating ksheera and ghrita into daily diets through palatable preparations is vital for achieving the benefits of Nithya Rasayana. By utilizing various preparations mentioned in classics individuals can enjoy these nutritious substances regularly, thereby supporting their overall health and well-being. This review aims to gather scientific evidence supporting the Ayurvedic principle of Ksheeraghritaabhyaso Rasayananam, which emphasizes the regular intake of ghee (Ghrita) and milk (Ksheera) for rejuvenation and longevity.